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mPNS for Carpal Tunnel Syndrome

mPNS for Carpal Tunnel Syndrome

Carpal tunnel syndrome (CTS) is compression of the median nerve at the wrist causing pain, numbness, and weakness in the hand. mPNS is a non-invasive neuromodulation therapy that targets peripheral nerves to reduce pain, modulate nerve excitability, and support functional recovery.

What is Carpal Tunnel Syndrome?

CTS results from increased pressure in the carpal tunnel that compresses the median nerve, producing sensory and motor symptoms in the thumb, index, middle, and radial half of the ring finger.

Common causes/risk factors: repetitive hand use, wrist anatomy, diabetes, thyroid disease, pregnancy, obesity, inflammatory conditions, and occupational exposures.

Common symptoms

  • Numbness, tingling, or burning in the thumb, index, middle fingers, and radial ring finger (often worse at night)
  • Hand weakness, dropping objects, reduced grip and pinch strength
  • Pain radiating from wrist into forearm or up the arm
  • Decreased fine motor coordination and clumsiness

Statistics (prevalence and burden)

CTS is common worldwide. A large meta-analysis pooled prevalence estimates around low-to-mid double digits depending on methods; population surveys report symptomatic prevalence roughly 10–15% with higher rates in women (examples vary by cohort and diagnostic criteria). [1][2]

CTS is a leading cause of work-related upper-limb disability and contributes substantially to healthcare visits and surgical decompressions.

How Carpal Tunnel Syndrome affects daily life

Limits work performance, especially in jobs requiring repetitive hand/wrist tasks (typing, assembly, manual labor)

Interferes with sleep (nocturnal symptoms), self-care (buttoning, writing), and hobbies (playing instruments, sports)

May lead to reduced productivity, time off work, and decline in quality of life if untreated

Common treatment options

Conservative Care

  • Wrist splinting (especially at night), activity modification, ergonomic adjustments
  • NSAIDs or short-term analgesics for symptom flares; corticosteroid injections for temporary relief in selected patients
  • Physical therapy: eccentric strengthening, stretching, and ergonomic training
  • Forearm braces or straps to unload the tendon during activity  

Other Treatment Options

When conservative care fails:
Surgical carpal tunnel release (open or endoscopic) to decompress the median nerve — effective for many patients with moderate/severe or progressive symptoms

Emerging and adjunctive options:
Peripheral nerve stimulation (implantable) and non-invasive neuromodulation techniques are under study as adjuncts or alternatives for patients seeking less-invasive options

What is mPNS and how it works

mPNS delivers focused magnetic pulses over the peripheral nerve region to modulate nerve excitability, reduce ectopic discharges, and decrease peripheral and central sensitization that contribute to pain and paresthesia. It is non-invasive and does not require implantation or injections.

Potential benefits for CTS:

Symptom reduction (numbness, paresthesia, pain) by altering aberrant nerve firing and improving nerve function environment

Improved hand function and tolerance for rehabilitation exercises and ergonomic retraining

Low systemic side-effect burden compared with long-term medication; outpatient, needle-free option for patients who prefer non-invasive care or wish to delay/avoid surgery

Useful alternative for patients who prefer to avoid injections or surgery

Often well tolerated with low complication rates

Typical course and expectations

    • Clinical assessment and diagnosis (history, exam, and often nerve conduction studies) before mPNS; screen for contraindications (e.g., certain implanted electronic devices).  
    • mPNS is delivered in a series of brief clinic sessions; many patients report gradual symptomatic improvement over days–weeks. Individual responses vary and best outcomes occur when mPNS is integrated with splinting, activity modification, and hand therapy.  

Schedule an evaluation

To learn if mPNS can help your golfer’s elbow, schedule a FREE consultation with our specialist experienced in neuromodulation and musculoskeletal care.

References

[1] Systematic review / meta-analysis on CTS prevalence: “Global and Regional Prevalence of Carpal Tunnel Syndrome: A Meta-Analysis” — Musculoskeletal Care; pooled prevalence estimates and regional data.

[2] Population study (symptomatic prevalence by sex): “Prevalence of Carpal Tunnel Syndrome in a General Population” — JAMA Neurology.

[3] Clinical guidance: American Academy of Orthopaedic Surgeons (AAOS) clinical practice guideline updates on CTS management and evidence-based recommendations (2024 news/release summarizing guideline updates)

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